Limin Zhang Selected Research

5- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamide

2/2022	TJ-M2010-5, A self-developed MyD88 inhibitor, attenuates liver fibrosis by inhibiting the NF-κB pathway.
8/2020	TJ-M2010-5, a novel MyD88 inhibitor, corrects R848-induced lupus-like immune disorders of B cells in vitro.
2/2019	Short-term use of MyD88 inhibitor TJ-M2010-5 prevents d-galactosamine/lipopolysaccharide-induced acute liver injury in mice.

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Limin Zhang Research Topics

Disease

42	Neoplasms (Cancer) 11/2022 - 09/2007
15	Inflammation (Inflammations) 09/2022 - 01/2011
9	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 08/2016
7	Obesity 01/2022 - 08/2013
7	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2013
6	Prostatic Neoplasms (Prostate Cancer) 11/2021 - 01/2013
6	Alzheimer Disease (Alzheimer's Disease) 11/2020 - 11/2015
5	Infections 07/2022 - 10/2017
5	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 11/2012
5	Body Weight (Weight, Body) 01/2022 - 01/2016
5	Ischemic Stroke 12/2021 - 01/2019
5	Non-alcoholic Fatty Liver Disease 04/2021 - 01/2015
5	Brain Ischemia (Cerebral Ischemia) 01/2020 - 08/2015
5	Parkinson Disease (Parkinson's Disease) 01/2017 - 01/2011
4	Human Influenza (Influenza) 07/2022 - 10/2017
4	Metabolic Diseases (Metabolic Disease) 01/2022 - 01/2017
4	Brain Diseases (Brain Disorder) 01/2019 - 01/2017
3	COVID-19 07/2022 - 01/2022
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/2021 - 12/2015
3	Adenocarcinoma of Lung 01/2021 - 01/2017
3	Hypertension (High Blood Pressure) 01/2021 - 11/2020
3	Epilepsy (Aura) 11/2016 - 11/2013
3	Seizures (Absence Seizure) 11/2016 - 11/2013
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2022 - 03/2013
2	Liver Cirrhosis (Hepatic Cirrhosis) 02/2022 - 02/2011
2	Ischemia 01/2022 - 01/2019
2	Weight Gain 01/2022 - 02/2016
2	Cognitive Dysfunction 07/2021 - 01/2021
2	Glioma (Gliomas) 01/2021 - 01/2021
2	Fatty Liver 04/2020 - 09/2016
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 02/2020 - 10/2015
2	Hemorrhagic Shock 02/2019 - 01/2014
2	Hepatocellular Carcinoma (Hepatoma) 10/2018 - 02/2011

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 07/2022 - 03/2013
9	Pharmaceutical PreparationsIBA 09/2022 - 09/2007
8	Biological ProductsIBA 01/2021 - 07/2008
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2014
7	MicroRNAs (MicroRNA)IBA 01/2019 - 03/2013
5	Fatty Acids (Saturated Fatty Acids)IBA 09/2022 - 12/2013
4	Peptides (Polypeptides)IBA 11/2022 - 02/2017
4	LigandsIBA 01/2022 - 01/2018
4	Messenger RNA (mRNA)IBA 11/2021 - 02/2017
4	GoldIBA 02/2016 - 03/2006
3	CytokinesIBA 10/2022 - 01/2016
3	Immune Checkpoint InhibitorsIBA 09/2022 - 01/2019
3	EnzymesIBA 09/2022 - 12/2020
3	5- (3- (4- (4- benzylpiperazin- 1- yl)- N- (4- phenylthiazol- 2- yl))propanamideIBA 02/2022 - 02/2019
3	Hemagglutinins (Hemagglutinin)IBA 01/2022 - 10/2017
3	Environmental Pollutants (Pollutants, Environmental)IBA 01/2022 - 11/2019
3	Long Noncoding RNAIBA 01/2021 - 08/2016
3	LipidsIBA 01/2021 - 12/2015
3	CeramidesIBA 01/2021 - 01/2015
3	Tyrosine Kinase InhibitorsIBA 11/2018 - 08/2017
3	ErbB Receptors (EGF Receptor)IBA 11/2018 - 08/2017
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018 - 09/2007
3	Phosphotransferases (Kinase)IBA 05/2017 - 02/2008
2	Bile Acids and Salts (Bile Acids)IBA 09/2022 - 04/2021
2	icariside IIBA 09/2022 - 08/2021
2	InterferonsIBA 09/2022 - 01/2022
2	VaccinesIBA 07/2022 - 01/2022
2	Serum AlbuminIBA 05/2022 - 12/2013
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 11/2018
2	Choline (Choline Chloride)IBA 01/2022 - 12/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 05/2017
2	fibrin fragment D (D-dimer)IBA 12/2021 - 01/2021
2	Therapeutic UsesIBA 11/2021 - 02/2018
2	LipopolysaccharidesIBA 11/2021 - 02/2021
2	Docetaxel (Taxotere)FDA Link 11/2021 - 01/2020
2	Volatile Fatty AcidsIBA 08/2021 - 01/2017
2	Acetates (Acetic Acid Esters)FDA Link 07/2021 - 01/2021
2	trichlorosucrose (sucralose)IBA 04/2021 - 02/2021
2	OligosaccharidesIBA 04/2021 - 02/2021
2	Metformin (Glucophage)FDA LinkGeneric 04/2021 - 02/2021
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 02/2021 - 04/2020
2	C-Reactive ProteinIBA 01/2021 - 04/2011
2	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 11/2020
2	AntioxidantsIBA 12/2020 - 02/2016
2	Folic Acid (Vitamin M)FDA LinkGeneric 12/2020 - 01/2011
2	HomocysteineIBA 12/2020 - 04/2011
2	Immunoglobulin G (IgG)IBA 09/2020 - 01/2019
2	Triglycerides (Triacylglycerol)IBA 04/2020 - 01/2016
2	trans-crotonin (CTN)IBA 02/2020 - 10/2015
2	TroponinIBA 02/2020 - 10/2015
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2019
2	Amino Acids FDA Link 01/2020 - 12/2013
2	Broadly Neutralizing AntibodiesIBA 01/2019 - 10/2017
2	RNA (Ribonucleic Acid)IBA 01/2019 - 02/2017
2	Oxygen (Dioxygen)IBA 01/2019 - 01/2017
2	GenisteinIBA 01/2019 - 06/2015
2	Antiviral Agents (Antivirals)IBA 01/2019 - 10/2017
2	Oseltamivir (Tamiflu)FDA Link 01/2019 - 10/2017
2	Inulin FDA Link 10/2018 - 10/2015

Therapy/Procedure

22	Therapeutics 09/2022 - 02/2008
6	Electrodes (Electrode) 01/2020 - 03/2006
4	Drug Therapy (Chemotherapy) 11/2021 - 01/2015
3	Immunotherapy 09/2022 - 02/2021
3	Stents 12/2021 - 01/2015
2	Oral Administration 09/2022 - 08/2021
2	Microelectrodes 01/2022 - 02/2016
2	Precision Medicine 07/2021 - 01/2021